Chlorothiazide should be used cautiously in patients with renal disease resulting in severe renal impairment because the drug decreases the glomerular. Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Diuril (Chlorothiazide). Chlorothiazide sodium for injection, USP is a diuretic and a vial containing: Chlorothiazide sodium equiva- . toxicity. Refer to the package insert for lithium.

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Diuril Oral Suspension mg/5mL, 8 oz. Bottle

For patients with difficulty swallowing, pacoage tablets may be crushed and mixed with fluid or the oral suspension may be used. Moderate Local anesthetics may cause additive hypotension in combination with antihypertensive agents.

CoQ10 use in combination with antihypertensive agents may lead to additional reductions in blood pressure in some individuals. Amphotericin B liposomal LAmB: It appears that the effects of thiazide diuretics on glycemic control are dose-related and low doses can be instituted without deleterious effects on glycemic control.

Hypokalemia may develop especially with brisk diuresis, when severe cirrhosis is present or after prolonged therapy.

Moderate When canagliflozin is initiated in patients already receiving diuretics, symptomatic hypotension can occur. Moderate Concomitant administration of methoxsalen and other photosensitizing agents, such as thiazide diuretics, can increase the incidence or severity of photsensitization from either compound.

Serotonin norepinephrine reuptake inhibitors: Dosage adjustments may be necessary. While no specific drug interactions have been identified with systemic agents and apraclonidine during clinical trials, it is theoretically possible that additive blood pressure reductions could occur when apraclonidine is combined with the use of antihypertensive agents.


Moderate Alemtuzumab may cause hypotension. If isoproterenol is used concomitantly with antihypertensives, the blood pressure should be monitored packate the administration of isoproterenol can compromise the effectiveness of antihypertensive agents.

Major Patients receiving thiazide diuretics during oprelvekin, rh-IL therapy are at increased risk for developing severe hypokalemia; close monitoring of fluid and electrolyte status is warranted during concurrent diuretic and oprelvekin therapy.

The potential reduction in blood pressure can precipitate orthostatic hypotension and associated dizziness, tachycardia, and syncope. Blood pressure and heart rates should be monitored closely to confirm that the desired antihypertensive effect is achieved. Electrolyte imbalances may occur while on these diuretics, which may in turn predispose patients to the cardiac effects of halofantrine.

Dilution Chlorothiazide – GlobalRPH

If indicated, dosage of the antihypertensive agents should be reduced. Patients should avoid excessive sunlight UV exposure and therapy should be discontinued if phototoxicity occurs. Use the smallest dosage necessary to achieve the required response. Moderate The potential for hypotension may be increased when coadministering nesiritide with antihypertensive agents. Moderate Concomitant use of medicines with potential to alter renal perfusion or function such as diuretics, may increase the risk of acute phosphate nephropathy in patients taking sodium phosphate monobasic monohydrate; sodium phosphate dibasic anhydrous.

Moderate Patients receiving diuretics or other agents to control fluid and electrolyte balance may require nisert adjustments while receiving octreotide due to additive effects. Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine: Do not use, thiazide diuretics generally not effective in this setting. May be given by slow IV injection or by IV infusion.


It is possible that additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. Thiazide diuretics can decrease the hypoglycemic effects of insulin by producing ddiuril increase in blood glucose levels. Although leading drug interaction texts differ in the potential for an interaction between diethylpropion and this group of antihypertensive agents, these effects are likely to be clinically significant and have been described in hypertensive patients on these medications.

Moderate Prazosin is well-known to produce a ‘first-dose’ phenomenon. In patients with renal disease, thiazides may precipitate azotemia.

Additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. Thiazides also decrease the elimination of calcium and uric acid.

In general, diuretics can worsen glucose tolerance and lipid abnormalities.

Thiazides may add to or potentiate the action of other antihypertensive drugs. Caution is advisable in patients receiving medications known to cause hyponatremia, such as diuretics.

We do not record any personal information entered above. Corticosteroids, ACTH — intensified electrolyte depletion, particularly hypokalemia.

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Coadministration increases the risk of too rapid correction of serum sodium. The reconstituted solution is clear and essentially free inert visible particles. Excessive hypotension during thiazide diuretic therapy can result in syncope.